Distribution of CYP2D6 polymorphism in the Middle Eastern region

Cytochrome P450 2D6 (CYP2D6) is an important drug-metabolizing enzyme involved in the pharmacokinetic metabolism of drugs. CYP2D6 gene is highly polymorphic, and the combination of its different alleles yields different phenotypes including extensive metabolizer (EM), intermediate metabolizer (IM),...

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Detalhes bibliográficos
Main Authors: Zahra Khalaj, Zohreh Baratieh, Parvaneh Nikpour, Hossein Khanahmad, Fariborz Mokarian, Rasoul Salehi, Mansoor Salehi
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2019-01-01
Colecção:Journal of Research in Medical Sciences
Assuntos:
allele frequency
cytochrome p450 2d6
middle east
Acesso em linha:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=61;epage=61;aulast=Khalaj
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