Upregulation of Ferroptosis-Related Fanconi Anemia Group D2 is a Poor Prognostic Factor and an Indicator of Tumor Immune Cell Infiltration in Lung Adenocarcinoma

Fanconi anemia (FA) group D2 (FANCD2) is a ferroptosis-related gene crucial for DNA damage repair and negative ferroptosis regulation. Our study aimed to evaluate its prognostic value as well as its association with ferroptosis and immune infiltration in lung adenocarcinoma (LUAD). Transcriptome seq...

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Detalhes bibliográficos
Main Authors: Jingtao Zhang, Dongli Wang, Xiubao Chen, Lingyun Ji, Minmin Yu, Minghao Guo, Dexin Zhang, Weida Chen, Fei Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Genetics
Assuntos:
FANCD2
lung adenocarcinoma
ferroptosis
tumor-infiltrating immune cells
biomarker
prognosis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2022.825685/full
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