Honokiol Induces Ferroptosis by Upregulating HMOX1 in Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is one of the malignant hematological cancers with high mortality. Finding a more effective and readily available treatment is of the utmost importance. Here, we aimed to identify the anti-leukemia effect of a natural small molecule compound honokiol on a panel of AML ce...

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Detalhes bibliográficos
Main Authors: Xingrong Lai, Yanhua Sun, Xuedi Zhang, Dan Wang, Jialing Wang, Haihua Wang, Yao Zhao, Xinling Liu, Xin Xu, Haoran Song, Wenjia Ping, Yanli Sun, Zhenbo Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Pharmacology
Assuntos:
honokiol
AML
ferroptosis
heme oxygenase (HO)-1
lipid peroxidation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.897791/full
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