The sigma-1 receptor: a regulator of cancer cell electrical plasticity?

Originally mistaken as an opioid receptor, the sigma 1 receptor (Sig1R) is a ubiquitous membrane protein that has been involved in many cellular processes. While the precise function of Sig1R has long remained mysterious, recent studies have shed light on its role and the molecular mechanisms trigge...

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Main Authors: David eCrottès, Hélène eGuizouarn, Patrick eMartin, Franck eBorgese, Olivier eSoriani
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013-07-01
Serija:Frontiers in Physiology
Teme:
Stress, Physiological
Cancer
chaperones
ion channels modulation
sigma-1 receptor
Online dostop:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00175/full
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