The sigma-1 receptor: a regulator of cancer cell electrical plasticity?

Originally mistaken as an opioid receptor, the sigma 1 receptor (Sig1R) is a ubiquitous membrane protein that has been involved in many cellular processes. While the precise function of Sig1R has long remained mysterious, recent studies have shed light on its role and the molecular mechanisms trigge...

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Detalhes bibliográficos
Main Authors: David eCrottès, Hélène eGuizouarn, Patrick eMartin, Franck eBorgese, Olivier eSoriani
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013-07-01
Colecção:Frontiers in Physiology
Assuntos:
Stress, Physiological
Cancer
chaperones
ion channels modulation
sigma-1 receptor
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00175/full
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