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Single-Cell Analyses of Human Eosinophils at High Resolution to Understand Compartmentalization and Vesicular Trafficking of Interferon-Gamma

Human eosinophils release numerous cytokines that are pre-synthesized and stored within their cytoplasmic-specific (secretory) granules. For example, high levels of interferon-gamma (IFN-γ) are constitutively expressed in these cells, but the intracellular compartments involved in the transport and...

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Detalhes bibliográficos
Main Authors: Lívia A. S. Carmo, Kennedy Bonjour, Lisa A. Spencer, Peter F. Weller, Rossana C. N. Melo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-07-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2018.01542/full
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