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Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes.

Dopaminergic nuclei in the basal ganglia are highly sensitive to damage from oxidative stress, inflammation, and environmental neurotoxins. Disruption of adenosine triphosphate (ATP)-dependent calcium (Ca2+) transients in astrocytes may represent an important target of such stressors that contribute...

詳細記述

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書誌詳細
主要な著者: Karin M Streifel, Albert L Gonzales, Briana De Miranda, Rola Mouneimne, Scott Earley, Ronald Tjalkens
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2014-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC4217743?pdf=render
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