Dopaminergic Neurotoxicants Cause Biphasic Inhibition of Purinergic Calcium Signaling in Astrocytes

Dopaminergic nuclei in the basal ganglia are highly sensitive to damage from oxidative stress, inflammation, and environmental neurotoxins. Disruption of adenosine triphosphate (ATP)-dependent calcium (Ca(2+)) transients in astrocytes may represent an important target of such stressors that contribu...

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Bibliographic Details
Main Authors: Streifel, Karin M., Gonzales, Albert L., De Miranda, Briana, Mouneimne, Rola, Earley, Scott, Tjalkens, Ronald
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217743/
https://ncbi.nlm.nih.gov/pubmed/25365260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110996
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