The Snake with the Scorpion’s Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus)

Millions of years of evolution have fine-tuned the ability of venom peptides to rapidly incapacitate both prey and potential predators. Toxicofera reptiles are characterized by serous-secreting mandibular or maxillary glands with heightened levels of protein expression. These glands are the core ana...

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Main Authors: Daryl C. Yang, Jennifer R. Deuis, Daniel Dashevsky, James Dobson, Timothy N. W. Jackson, Andreas Brust, Bing Xie, Ivan Koludarov, Jordan Debono, Iwan Hendrikx, Wayne C. Hodgson, Peter Josh, Amanda Nouwens, Gregory J. Baillie, Timothy J. C. Bruxner, Paul F. Alewood, Kelvin Kok Peng Lim, Nathaniel Frank, Irina Vetter, Bryan G. Fry
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2016-10-01
Serija:Toxins
Teme:
toxicofera
venom
evolution
neurotoxin
sodium channel
pharmacology
Online dostop:http://www.mdpi.com/2072-6651/8/10/303
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