Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains

Snake venom metalloproteases (SVMP) are composed of five domains: signal peptide, propeptide, metalloprotease, disintegrin, and cysteine-rich. Secreted toxins are typically combinatorial variations of the latter three domains. The SVMP-encoding genes of Psammophis mossambicus venom are unique in con...

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Hauptverfasser: Brust, Andreas, Sunagar, Kartik, Undheim, Eivind A.B., Vetter, Irina, Yang, Daryl C., Casewell, Nicholas R., Jackson, Timothy N. W., Koludarov, Ivan, Alewood, Paul F., Hodgson, Wayne C., Lewis, Richard J., King, Glenn F., Antunes, Agostinho, Hendrikx, Iwan, Fry, Bryan G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591658/
https://ncbi.nlm.nih.gov/pubmed/23242553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.023135
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