Differential Expression of Sirtuin Family Members in the Developing, Adult, and Aged Rat Brain

The sirtuins are NAD+-dependent protein deacetylases and/or ADP-ribosyltransferases that play roles in metabolic homeostasis, stress response and potentially aging. This enzyme family resides in different subcellular compartments, and acts on a number of different targets in the nucleus, cytoplasm a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Elena eSidorova-Darmos, Robert G. Wither, Natalya eShulyakova, Carl eFisher, Melanie eRatnam, Michelle eAarts, Lothar eLilge, Philippe P. Monnier, James Howard Eubanks
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2014-12-01
Sarja:Frontiers in Aging Neuroscience
Aiheet:
Aging
Brain
Sirtuins
development
Neuron
astrocyte
Linkit:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00333/full
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