UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway

Human hepatocellular carcinoma (HCC) has a high mortality rate because of the dearth of effective treatments. Multiple studies have shown that overexpression of UPF1, a key nonsense-mediated mRNA decay (NMD) factor, reduces HCC growth through various cell signaling pathways. However, the mechanism b...

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Detalhes bibliográficos
Principais autores: Suman Lee, Yukyung Hwang, Tae Hun Kim, Jaemin Jeong, Dongho Choi, Jungwook Hwang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-03-01
coleção:Biomedicines
Assuntos:
UPF1
hepatocellular carcinoma
posttranscriptional regulation
DUSP1
Acesso em linha:https://www.mdpi.com/2227-9059/10/4/793
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