Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses.

Rheumatoid arthritis (RA) is a major cause of adult chronic inflammatory arthritis and a typical complex trait. Although several genetic determinants have been identified, they account for only a part of the genetic susceptibility. We conducted a genome-wide association study of RA in Japanese using...

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Detalhes bibliográficos
Main Authors: Chikashi Terao, Koichiro Ohmura, Masaki Katayama, Meiko Takahashi, Miki Kokubo, Gora Diop, Yoshinobu Toda, Natsuki Yamamoto, Human Disease Genomics Working Group, Rheumatoid Arthritis (RA) Clinical and Genetic Study Consortium, Reiko Shinkura, Masakazu Shimizu, Ivo Gut, Simon Heath, Inga Melchers, Toshiaki Manabe, Mark Lathrop, Tsuneyo Mimori, Ryo Yamada, Fumihiko Matsuda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3108877?pdf=render
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