A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production

BACKGROUND: A previous study revealed the association between susceptibility to Takayasu arteritis (TAK) and a single nucleotide polymorphism (SNP) rs6871626 located in IL12B, which encodes interleukin (IL)-12p40, a common component of IL-12p70 and IL-23. We investigated the expression of these cyto...

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Pubblicato in:Arthritis Res Ther
Autori principali: Nakajima, Toshiki, Yoshifuji, Hajime, Shimizu, Masakazu, Kitagori, Koji, Murakami, Kosaku, Nakashima, Ran, Imura, Yoshitaka, Tanaka, Masao, Ohmura, Koichiro, Matsuda, Fumihiko, Terao, Chikashi, Mimori, Tsuneyo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585951/
https://ncbi.nlm.nih.gov/pubmed/28874185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1408-8
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