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Structural requirements for Yersinia YopJ inhibition of MAP kinase pathways.
MAPK signaling cascades are evolutionally conserved. The bacterial effector, YopJ, uses the unique activity of Ser/Thr acetylation to inhibit the activation of the MAPK kinase (MKK) and prevent activation by phosphorylation. YopJ is also able to block yeast MAPK signaling pathways using this mechani...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science (PLoS)
2008-01-01
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| Collection: | PLoS ONE |
| Accès en ligne: | http://europepmc.org/articles/PMC2147050?pdf=render |
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