Serum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry

Toxoplasma gondii is an obligate intracellular parasite causing severe diseases in immunocompromised individuals and congenitally infected neonates, such as encephalitis and chorioretinitis. This study aimed to determine whether serum metabolic profiling can (i) identify metabolites associated with...

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Библиографические подробности
Главные авторы: Chun-Xue Zhou, Wei Cong, Xiao-Qing Chen, Shen-Yi He, Hany M. Elsheikha, Xing-Quan Zhu
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018-01-01
Серии:Frontiers in Microbiology
Предметы:
Toxoplasma gondii
oocyst
LC-MS/MS
metabolomics
mouse model
Online-ссылка:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02612/full
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