Serum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry

Toxoplasma gondii is an obligate intracellular parasite causing severe diseases in immunocompromised individuals and congenitally infected neonates, such as encephalitis and chorioretinitis. This study aimed to determine whether serum metabolic profiling can (i) identify metabolites associated with...

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Bibliographic Details
Main Authors: Chun-Xue Zhou, Wei Cong, Xiao-Qing Chen, Shen-Yi He, Hany M. Elsheikha, Xing-Quan Zhu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Microbiology
Subjects:
Toxoplasma gondii
oocyst
LC-MS/MS
metabolomics
mouse model
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02612/full
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