Design of Oligonucleotide Carriers: Importance of Polyamine Chain Length

Amine containing polymers are extensively studied as special carriers for short-chain RNA (13⁻25 nucleotides), which are applied as gene silencing agents in gene therapy of various diseases including cancer. Elaboration of the oligonucleotide carriers requires knowledge about peculiarities...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vadim V. Annenkov, Uma Maheswari Krishnan, Viktor A. Pal’shin, Stanislav N. Zelinskiy, Gayathri Kandasamy, Elena N. Danilovtseva
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2018-11-01
Saila:Polymers
Gaiak:
polymeric amines
oligonucleotides
critical length
grafted polyamines
gene delivery
Sarrera elektronikoa:https://www.mdpi.com/2073-4360/10/12/1297
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