H-Bond Mediated Phase-Transfer Catalysis: Enantioselective Generating of Quaternary Stereogenic Centers in β-Keto Esters

In this work, we would like to present the development of a highly optimized method for generating the quaternary stereogenic centers in β-keto esters. This enantioselective phase-transfer alkylation catalyzed by hybrid <i>Cinchona</i> catalysts allows for the efficient generation of the...

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Main Authors: Patryk Niedbała, Maciej Majdecki, Piotr Grodek, Janusz Jurczak
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-04-01
Series:Molecules
Assuntos:
phase-transfer catalysis
organocatalysis
enantioselectivity
<i>Cinchona</i> catalysts
alkylation
Acceso en liña:https://www.mdpi.com/1420-3049/27/8/2508
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