Hypoxia-reprogrammed regulatory group 2 innate lymphoid cells promote immunosuppression in pancreatic cancer

Summary: Background: Previously, we uncovered a patient subgroup with highly malignant pancreatic cancer with serum markers CEA+/CA125+/CA19-9 ≥ 1000 U/mL (triple-positive, TP). However, the underlying immunosuppressive mechanism in the tumor immune microenvironment (TIME) of this subgroup is still...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Longyun Ye, Kaizhou Jin, Zhenyu Liao, Zhiwen Xiao, Huaxiang Xu, Xuan Lin, Hao Li, Tianjiao Li, Wuhu Zhang, Xuan Han, Wenquan Wang, Heli Gao, Liang Liu, Weiding Wu, Xianjun Yu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2022-05-01
श्रृंखला:EBioMedicine
विषय:
Group 2 innate lymphoid cells (ILC2s)
Pancreatic ductal adenocarcinoma (PDAC)
Hypoxia
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S2352396422002006
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