Hypoxia-reprogrammed regulatory group 2 innate lymphoid cells promote immunosuppression in pancreatic cancer

Summary: Background: Previously, we uncovered a patient subgroup with highly malignant pancreatic cancer with serum markers CEA+/CA125+/CA19-9 ≥ 1000 U/mL (triple-positive, TP). However, the underlying immunosuppressive mechanism in the tumor immune microenvironment (TIME) of this subgroup is still...

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Detalhes bibliográficos
Main Authors: Longyun Ye, Kaizhou Jin, Zhenyu Liao, Zhiwen Xiao, Huaxiang Xu, Xuan Lin, Hao Li, Tianjiao Li, Wuhu Zhang, Xuan Han, Wenquan Wang, Heli Gao, Liang Liu, Weiding Wu, Xianjun Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-05-01
Colecção:EBioMedicine
Assuntos:
Group 2 innate lymphoid cells (ILC2s)
Pancreatic ductal adenocarcinoma (PDAC)
Hypoxia
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396422002006
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