Host immune response mediates changes in cagA copy number and virulence potential of Helicobacter pylori

Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV secretion system (T4SS) and its effector CagA encoded on the cag pathogenicity Island (cagPAI) increases the risk. H. pylori PMSS1 has a multi-cagA genotype, modulating cagA copy number dynamically from...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sungil Jang, Lori M. Hansen, Hanfu Su, Jay V. Solnick, Jeong-Heon Cha
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis Group 2022-12-01
श्रृंखला:Gut Microbes
विषय:
Helicobacter pylori
cagA
cagY
virulence
immune response
ऑनलाइन पहुंच:https://www.tandfonline.com/doi/10.1080/19490976.2022.2044721
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