Molecular profiling of lung cancer specimens and liquid biopsies using MALDI-TOF mass spectrometry

Abstract Background Identification of predictive molecular alterations in lung adenocarcinoma is essential for accurate therapeutic decisions. Although several molecular approaches are available, a number of issues, including tumor heterogeneity, frequent material scarcity, and the large number of l...

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Hlavní autoři: Eleonora Bonaparte, Chiara Pesenti, Laura Fontana, Rossella Falcone, Leda Paganini, Anna Marzorati, Stefano Ferrero, Mario Nosotti, Paolo Mendogni, Claudia Bareggi, Silvia Maria Sirchia, Silvia Tabano, Silvano Bosari, Monica Miozzo
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-01-01
Edice:Diagnostic Pathology
Témata:
Molecular diagnostics
MALDI-TOF mass spectrometry
Non-small cell lung cancer
Targeted therapy
Tumor genotyping
On-line přístup:http://link.springer.com/article/10.1186/s13000-017-0683-7
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