LINC00669 insulates the JAK/STAT suppressor SOCS1 to promote nasopharyngeal cancer cell proliferation and invasion

Abstract Nasopharyngeal carcinoma (NPC) is an epithelial cancer emerging from the lining of nasopharyngeal mucosa, with extremely frequent occurrence in east and southeast Asia. For the purpose of exploring roles of the dysregulated long non-coding RNA (lncRNA) in NPC, we identified a novel lncRNA L...

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Autori principali: Xiang Qing, Guo-lin Tan, Huo-wang Liu, Wei Li, Jin-gang Ai, Shan-shan Xiong, Meng-qing Yang, Tian-sheng Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-08-01
Serie:Journal of Experimental & Clinical Cancer Research
Soggetti:
Nasopharyngeal carcinoma
Long non-coding RNA
LINC00669
JAK/STAT
SOCS1
STAT1
Accesso online:http://link.springer.com/article/10.1186/s13046-020-01674-z
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