Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice

Amyloidopathy involves the accumulation of insoluble amyloid β (Aβ) species in the brain’s parenchyma and is a key histopathological hallmark of Alzheimer’s disease (AD). Work on transgenic mice that overexpress A suggests that elevated A levels in the brain are associated with aberrant epileptifo...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Francesco eTamagnini, Janet eNovelia, Talitha L Kerrigan, Jon T Brown, Krasimira eTsaneva-Atanasova, Andrew D Randall
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2015-10-01
Серии:Frontiers in Cellular Neuroscience
Предметы:
Hippocampus
Ageing
hyperexcitability
Capacitance
Membrane properties
firing frequency
Online-ссылка:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00372/full
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы