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In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.
Acute kidney injury is a major clinical problem and advanced age is associated with ineffective renal regeneration and poor functional outcome. Data from kidney injury models suggest that a loss of tubular epithelial proliferation contributes to a decrease in renal repair capacity with aging, but ag...
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Auteurs principaux: | , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science (PLoS)
2014-01-01
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Collection: | PLoS ONE |
Accès en ligne: | http://europepmc.org/articles/PMC3913727?pdf=render |
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