In Vivo and In Vitro Analysis of Age-Associated Changes and Somatic Cellular Senescence in Renal Epithelial Cells

Acute kidney injury is a major clinical problem and advanced age is associated with ineffective renal regeneration and poor functional outcome. Data from kidney injury models suggest that a loss of tubular epithelial proliferation contributes to a decrease in renal repair capacity with aging, but ag...

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Bibliographic Details
Main Authors: Berkenkamp, Birgit, Susnik, Nathan, Baisantry, Arpita, Kuznetsova, Inna, Jacobi, Christoph, Sörensen-Zender, Inga, Broecker, Verena, Haller, Hermann, Melk, Anette, Schmitt, Roland
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913727/
https://ncbi.nlm.nih.gov/pubmed/24505380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088071
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