Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins

Porcine circovirus type 2 (PCV2) is the etiological agent of porcine circovirus diseases and porcine circovirus-associated diseases (PCVDs/PCVADs). However, the pathogenesis of PCV2 is not fully understood. We previously found that 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is negativel...

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Detalhes bibliográficos
Main Authors: Ting Ouyang, Guyu Niu, Yifang Zhang, Xiaohua Liu, Xinwei Zhang, Shiqi Zhang, Yulu Geng, Daxin Pang, Hongsheng Ouyang, Linzhu Ren
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-06-01
Colecção:Viruses
Assuntos:
porcine circovirus type 2 (PCV2)
3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR)
adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK)
protein phosphatase 2 (PP2A)
interaction
Acesso em linha:https://www.mdpi.com/1999-4915/11/6/544
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