Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice

<p>Abstract</p> <p>Background</p> <p>Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance following suboptimal t...

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Bibliographic Details
Main Authors: Bacon Teresa H, Halsey Wendy S, Wittrock Robert J, Nguyen Tammy T, Quail Matthew R, Dennis Shelley A, Bartus H Ron, Sarisky Robert T, Leary Jeffry J, Sutton David
Format: Artigo
Language:Inglês
Published: BMC 2001-12-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/1/24
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