Genome adaptive evolution of Lactobacillus casei under long-term antibiotic selection pressures

Abstract Background The extensive use of antibiotics in medicine has raised serious concerns about biosafety. However, the effect of antibiotic application on the adaptive evolution of microorganisms, especially to probiotic bacteria, has not been well characterized. Thus, the objective of the curre...

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Bibliographic Details
Main Authors: Jicheng Wang, Xiao Dong, Yuyu Shao, Huiling Guo, Lin Pan, Wenyan Hui, Lai-Yu Kwok, Heping Zhang, Wenyi Zhang
Format: Artigo
Language:Inglês
Published: BMC 2017-04-01
Series:BMC Genomics
Subjects:
Lactobacillus casei Zhang
Amoxicillin
Gentamicin
Biosafety
Online Access:http://link.springer.com/article/10.1186/s12864-017-3710-x
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