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Genome adaptive evolution of Lactobacillus casei under long-term antibiotic selection pressures

Abstract Background The extensive use of antibiotics in medicine has raised serious concerns about biosafety. However, the effect of antibiotic application on the adaptive evolution of microorganisms, especially to probiotic bacteria, has not been well characterized. Thus, the objective of the curre...

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Detalhes bibliográficos
Main Authors: Jicheng Wang, Xiao Dong, Yuyu Shao, Huiling Guo, Lin Pan, Wenyan Hui, Lai-Yu Kwok, Heping Zhang, Wenyi Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-04-01
Colecção:BMC Genomics
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Acesso em linha:http://link.springer.com/article/10.1186/s12864-017-3710-x
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