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An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: functional, metabolic, and differential network analysis.

Estrogen exerts diverse biological effects in multiple tissues in both animals and humans. Much of the accumulated knowledge on the role of estrogen receptor (ER) in the heart has been obtained from studies using ovariectomized mice, whole body ER gene knock-out animal models, ex vivo heart studies,...

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Auteurs principaux: Sriram Devanathan, Timothy Whitehead, George G Schweitzer, Nicole Fettig, Attila Kovacs, Kenneth S Korach, Brian N Finck, Kooresh I Shoghi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2014-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC4085004?pdf=render
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