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Time-Course of Alterations in Myocardial Glucose Utilization in the Zucker Diabetic Fatty (ZDF) Rat with Correlation to Gene Expression of Glucose Transporters: A Small Animal PET Investigation

OBJECTIVE: Diabetic cardiomyopathy is associated with abnormalities in glucose metabolism. We evaluated myocardial glucose metabolism in a rodent model of Type 2 Diabetes (T2D), namely the Zucker Diabetic Rat (ZDF), and validated PET measures of glucose uptake against gene and protein expression of...

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Detalhes bibliográficos
Main Authors: Shoghi, Kooresh I., Gropler, Robert J., Sharp, Terry, Herrero, Pilar, Fettig, Nicole, Su, Yi, Mitra, Mayurranjan S., Kovacs, Attila, Finck, Brian N., Welch, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857655/
https://ncbi.nlm.nih.gov/pubmed/18632819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.051672
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