PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype

During tumorigenesis, macrophages are recruited by tumors and orientated towards a pro-tumoral phenotype. One of the main anti-tumoral immunotherapy consists of their re-polarization in an anti-tumoral phenotype. We have demonstrated that the inhibition of proprotein convertase 1/3 combined with TLR...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Franck Rodet, Alice Capuz, Bilgehan-Aybike Ozcan, Rémy Le Beillan, Antonella Raffo-Romero, Firas Kobeissy, Marie Duhamel, Michel Salzet
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2019-11-01
סדרה:Cells
נושאים:
anti-tumoral immunotherapy
macrophages
proprotein convertase 1/3
tlr4 desensitization
il-10 pro-tumoral effect
גישה מקוונת:https://www.mdpi.com/2073-4409/8/12/1490
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים