PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype

During tumorigenesis, macrophages are recruited by tumors and orientated towards a pro-tumoral phenotype. One of the main anti-tumoral immunotherapy consists of their re-polarization in an anti-tumoral phenotype. We have demonstrated that the inhibition of proprotein convertase 1/3 combined with TLR...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Franck Rodet, Alice Capuz, Bilgehan-Aybike Ozcan, Rémy Le Beillan, Antonella Raffo-Romero, Firas Kobeissy, Marie Duhamel, Michel Salzet
التنسيق: Artigo
اللغة:Inglês
منشور في: MDPI AG 2019-11-01
سلاسل:Cells
الموضوعات:
anti-tumoral immunotherapy
macrophages
proprotein convertase 1/3
tlr4 desensitization
il-10 pro-tumoral effect
الوصول للمادة أونلاين:https://www.mdpi.com/2073-4409/8/12/1490
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة