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ProNGF derived from rat sciatic nerves downregulates neurite elongation and axon specification in PC12 cells
Several reports have shown that a sciatic nerve conditioned media (CM) causes neuronal-like differentiation in PC12 cells. This differentiation is featured by neurite outgrowth, which are exclusively dendrites, without axon or sodium current induction. In previous studies, our group reported that th...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Frontiers Media S.A.
2015-09-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00364/full |
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