Does positioning of chromosomes 8 and 21 in interphase drive t(8;21) in acute myelogenous leukemia?

The impact of chromosome architecture in the formation of chromosome aberrations is a recent finding of interphase directed molecular cytogenetic studies. There evidence was provided that disease specific chromosomal translocations could be due to tissue specific genomic organization. In a recent sm...

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Detalhes bibliográficos
Main Authors: Moneeb A.K. Othman, Amelie Lier, Susann Junker, Philipp Kempf, Franziska Dorka, Erich Gebhart, Frenny J. Sheth, Beata Grygalewicz, Samarth Bhatt, Anja Weise, Kristin Mrasek, Thomas Liehr, Marina Manvelyan
Formato: Artigo
Idioma:Inglês
Publicado em: Pensoft Publishers 2012-10-01
Colecção:BioDiscovery
Assuntos:
interphase chromosome (genome) organization
forma
Acesso em linha:https://biodiscovery.pensoft.net/article/8934/download/pdf/
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