Multifunctional selenium nanoparticles with Galangin-induced HepG2 cell apoptosis through p38 and AKT signalling pathway

The morbidity and mortality of hepatocellular carcinoma, the most common cancer, are increasing continuously worldwide. Galangin (Ga) has been demonstrated to possess anti-cancer effect, but the efficacy of Ga was limited by its low permeability and poor solubility. To develop aqueous formulation an...

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Bibliographic Details
Main Authors: Yinghua Li, Min Guo, Zhengfang Lin, Mingqi Zhao, Yu Xia, Changbing Wang, Tiantian Xu, Bing Zhu
Format: Artigo
Language:Inglês
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
selenium nanoparticles
galangin
caspase-3
reactive oxygen species
apoptosis
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180509
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