gyrA and parC mutations in fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Kenya

Abstract Background Phenotypic fluoroquinolone resistance was first reported in Western Kenya in 2009 and later in Coastal Kenya and Nairobi. Until recently gonococcal fluoroquinolone resistance mechanisms in Kenya had not been elucidated. The aim of this paper is to analyze mutations in both gyrA a...

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Detalhes bibliográficos
Main Authors: Mary Wandia Kivata, Margaret Mbuchi, Fredrick Lunyagi Eyase, Wallace Dimbuson Bulimo, Cecilia Katunge Kyanya, Valerie Oundo, Simon Wachira Muriithi, Ben Andagalu, Wilton Mwema Mbinda, Olusegun O. Soge, R. Scott McClelland, Willy Sang, James D. Mancuso
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-04-01
Colecção:BMC Microbiology
Assuntos:
Fluoroquinolones
Antimicrobial resistance (AMR)
Neisseria gonorrhoeae
Mutation
Quinolone resistant determining regions (QRDR)
Acesso em linha:http://link.springer.com/article/10.1186/s12866-019-1439-1
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