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Secreted hCLCA1 is a signaling molecule that activates airway macrophages.

The CLCA gene family produces both secreted and membrane-associated proteins that modulate ion-channel function, drive mucus production and have a poorly understood pleiotropic effect on airway inflammation. The primary up-regulated human CLCA ortholog in airway inflammation is hCLCA1. Here we show...

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Bibliografiska uppgifter
Huvudupphovsmän: John C H Ching, Liubov Lobanova, Matthew E Loewen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC3861482?pdf=render
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