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Pedal to the Metal: Nuclear Splicing Bodies Turbo-Charge VSG mRNA Production in African Trypanosomes

The African trypanosome Trypanosoma brucei is a parasite of the mammalian bloodstream and tissues, where an antigenically variable Variant Surface Glycoprotein (VSG) coat protects it from immune attack. This dense layer comprised of ∼107 VSG proteins, makes VSG by far the most abundant mRNA (7–10% t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: James Budzak, Gloria Rudenko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2022-04-01
Cyfres:Frontiers in Cell and Developmental Biology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fcell.2022.876701/full
Tagiau: Ychwanegu Tag
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