Extracellular vesicular microRNAs as potential biomarker for early detection of doxorubicin‐induced cardiotoxicity

Abstract Background Long‐term use of doxorubicin (DOX) is limited by cumulative dose‐dependent cardiotoxicity. Objectives Identify plasma extracellular vesicle (EV)‐associated microRNAs (miRNAs) as a biomarker for cardiotoxicity in dogs by correlating changes with cardiac troponin I (cTnI) concentra...

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Detalhes bibliográficos
Main Authors: Amelie Beaumier, Sally R. Robinson, Nicholas Robinson, Katherine E. Lopez, Dawn M. Meola, Lisa G. Barber, Barret J. Bulmer, Jerome Calvalido, John E. Rush, Ashish Yeri, Saumya Das, Vicky K. Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-05-01
Colecção:Journal of Veterinary Internal Medicine
Assuntos:
chemotherapy
echocardiogram
ejection fraction
hemangiosarcoma
troponin
Acesso em linha:https://doi.org/10.1111/jvim.15762
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