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Antidepressant-Like Effect of Venlafaxine Is Abolished in μ-Opioid Receptor–Knockout Mice

Although the opioid system is known to modulate depression-like behaviors, its role in the effects of antidepressants is not yet clear. We investigated the role of μ-opioid receptors (MOPs) in the effects of venlafaxine, a serotonin and norepinephrine reuptake inhibitor, in the forced swim test usin...

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Main Authors: Soichiro Ide, Shunsuke Fujiwara, Masayuki Fujiwara, Ichiro Sora, Kazutaka Ikeda, Masabumi Minami, George R. Uhl, Kumatoshi Ishihara
格式: Artigo
語言:Inglês
出版: Elsevier 2010-01-01
叢編:Journal of Pharmacological Sciences
在線閱讀:http://www.sciencedirect.com/science/article/pii/S1347861319308862
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