Abolished thermal and mechanical antinociception but retained visceral chemical antinociception induced by butorphanol in μ-opioid receptor knockout mice

Butorphanol is hypothesized to induce analgesia via opioid pathways, although the precise mechanisms for its effects remain unknown. In this study, we investigated the role of the μ-opioid receptor (MOP) in thermal, mechanical, and visceral chemical antinociception induced by butorphanol using MOP k...

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Hlavní autoři: Ide, Soichiro, Minami, Masabumi, Ishihara, Kumatoshi, Uhl, George R., Satoh, Masamichi, Sora, Ichiro, Ikeda, Kazutaka
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769935/
https://ncbi.nlm.nih.gov/pubmed/18417173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.03.008
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