Short-term effects of Lumacaftor/Ivacaftor (Orkambi™) on exertional symptoms, exercise performance, and ventilatory responses in adults with cystic fibrosis

Abstract Rationale Lumacaftor/ivacaftor (LUM/IVA) modestly improves lung function following 1 month of treatment but it is unknown if this translates into improvements in exercise endurance and exertional symptoms. Methods Adult CF participants completed a symptom-limited constant load cycling test...

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Hauptverfasser: Bradley S. Quon, Andrew H. Ramsook, Satvir S. Dhillon, Reid A. Mitchell, Kyle G. Boyle, Pearce G. Wilcox, Jordan A. Guenette
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-06-01
Schriftenreihe:Respiratory Research
Online Zugang:http://link.springer.com/article/10.1186/s12931-020-01406-z
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