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Vitamin C controls neuronal necroptosis under oxidative stress

Under physiological conditions, vitamin C is the main antioxidant found in the central nervous system and is found in two states: reduced as ascorbic acid (AA) and oxidized as dehydroascorbic acid (DHA). However, under pathophysiological conditions, AA is oxidized to DHA. The oxidation of AA and sub...

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Detalhes bibliográficos
Main Authors: Luciano Ferrada, María Jose Barahona, Katterine Salazar, Peter Vandenabeele, Francisco Nualart
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-01-01
Colecção:Redox Biology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231719313448
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