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MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation

The molecules and mechanisms pertinent to the low immunogenicity of undifferentiated embryonic stem cells (ESCs) remain poorly understood. Here, we provide evidence that milk fat globule epidermal growth factor 8 (MFG-E8) is a vital mediator in this phenomenon and directly suppresses T cell immune r...

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Detalhes bibliográficos
Main Authors: Yuan Tan, Bodour AlKhamees, Deyong Jia, Li Li, Jean-François Couture, Daniel Figeys, Masahisa Jinushi, Lisheng Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-11-01
Colecção:Stem Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213671115002672
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