An Undergraduate Laboratory Exploring Mutational Mechanisms in Escherichia coli Based on the Luria-Delbrück Experiment

ABSTRACT Understanding the mechanism for DNA mutations is a key concept in most genetics and microbiology courses. In addition, understanding that most mutations occur prior to exposure to selection is an important yet often difficult concept for students to grasp. We developed an undergraduate labo...

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Detalhes bibliográficos
Main Authors: Elizabeth A. Hutchison, Abigail Scheffler, Kevin T. Militello, Josephine Reinhardt, Hristina Nedelkovska, Varuni K. Jamburuthugoda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2022-04-01
Colecção:Journal of Microbiology & Biology Education
Assuntos:
mutation
Luria-Delbrück
Escherichia coli
genetics
antibiotic resistance
mismatch repair
Acesso em linha:https://journals.asm.org/doi/10.1128/jmbe.00211-21
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