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Trabectedin – the DNA minor groove binder
Trabectedin (ET-743, Yondelis) is an alkaloid that was originally isolated from the Caribbean Sea squirt, Ecteinascidia turbinata and is now produced synthetically. Its chemical structure consists in three fused tetrahydroisoquinoline rings. Two of them, A and B, binds covalently to guanine residues...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Russo |
| Publicado em: |
ABV-press
2015-06-01
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| coleção: | Uspehi Molekulârnoj Onkologii |
| Assuntos: | |
| Acesso em linha: | https://umo.abvpress.ru/jour/article/view/24 |
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