GB Virus C E2 Inhibits PD-1-Mediated T Cell Signaling Dysfunction during Chronic Viral Infection

Background: Program death receptor 1 (PD-1) is a co-inhibitory receptor that is upregulated and contributes to T cell dysfunction (exhaustion) during chronic viral infections, including HIV and HCV. GB virus C (GBV-C) is a persistent human virus, and co-infection is associated with reduced immune ac...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Nirjal Bhattarai, Jennifer L. Welch, Jinhua Xiang, Muthu Saravanan Manoharan, Jeffrey A. Martinson, Alan L. Landay, Sunil K. Ahuja, James H. McLinden, Jack T. Stapleton
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI AG 2020-06-01
Serie:Proceedings
Ämnen:
GBV-C
PD-1
T cell exhaustion
HIV
Länkar:https://www.mdpi.com/2504-3900/50/1/62
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk