The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation.

Translation initiation factor eIF4E mediates mRNA selection for protein synthesis via the mRNA 5'cap. A family of binding proteins, termed the 4E-BPs, interact with eIF4E to hinder ribosome recruitment. Mechanisms underlying mRNA specificity for 4E-BP control remain poorly understood. Saccharom...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lydia M Castelli, David Talavera, Christopher J Kershaw, Sarah S Mohammad-Qureshi, Joseph L Costello, William Rowe, Paul F G Sims, Christopher M Grant, Simon J Hubbard, Mark P Ashe, Graham D Pavitt
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2015-05-01
Collection:PLoS Genetics
Accès en ligne:http://europepmc.org/articles/PMC4431810?pdf=render
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires